Melbourne Cup 2025: Jamie Melham follows in Michelle Payne’s footsteps with win aboard Half Yours


We need clarity on big pharma’s tax breaks | Letters
The outgoing chief executive of the pharmaceutical company GSK says the NHS should pay more for its drugs, in order to create “the right commercial environment” and ensure “patient access to innovation” (UK must reform drug pricing to become life sciences superpower, says GSK boss, 29 October).Our research shows that UK taxpayers are already paying handsomely for “patient access to innovation” through the £3.4bn in tax relief on profits of patented drugs that the UK has granted GSK via the UK’s “patent box” tax regime. This includes £486m in 2024 alone – larger than the entire budget of the Biotechnology and Biological Sciences Research Council, the UK’s main bioscience innovation funder.HMRC even granted UK tax relief to GSK on profits of a lupus drug, which for several years was unavailable to UK lupus sufferers, due to the price that GSK demanded from the NHS (£769

UK factories return to growth after JLR restarts operations; US manufacturing exports hit by tariffs – as it happened
UK manufacturing output has expanded for the first time in a year, helped by the restart of production at Jaguar Land Rover following its recent cyberhack.The latest poll of purchasing managers at UK factories, just released by S&P Global, shows that manufacturing output rose for the first time in a year in October.S&P Global reports that production volumes rose in the consumer and intermediate goods industries, partly due to a boost from the staged restarting of production at JLR last month.This helped to lift the wider UK Manufacturing Purchasing Managers’ Index to a 12-month high of 49.7 in October, up from 46

Australia’s richest person Gina Rinehart spotted at Donald Trump’s Halloween party
Australia’s richest person, Gina Rinehart, has been spotted at Donald Trump’s Halloween party at his Mar-a-Lago resort.The mining billionaire, who has never shied from publicly praising the controversial two-time US president, was seen speaking at Trump’s ear while he read a piece of paper in a social media post at the lavish affair at the weekend, as first reported by the Nine newspapers.The image, posted by the former US attorney for the District of Columbia, Jeanine Pirro, also included the US secretary of state, Marco Rubio.The 1920s, Great Gatsby-themed party also reportedly attracted the One Nation leader, Pauline Hanson, who the Nine newspapers claimed was seen in a private story on Instagram.Sign up: AU Breaking News emailHanson’s office confirmed to Guardian Australia that the senator is absent from the upper house this week because she is in the US

Victims robbed of £4bn in ‘insulting’ car loan redress scheme, say claims firms
Victims of the car loans scandal could miss out on more than £4bn in compensation if the City regulator ploughs ahead with plans for an “insulting” interest rate in its redress scheme, consumer groups and claims firms say.The Financial Conduct Authority (FCA) has been accused of offering a reduced rate of interest which will be added to compensation from banks for borrowers caught up in the car loan commissions scandal.Claims law firms and consumer groups say borrowers should be offered the same terms as Marcus Johnson: the sole driver whose case was upheld by the supreme court in a landmark case in August.While the terms of the final payout are sealed, Johnson is widely believed by industry experts to have received about 7% interest on his compensation package, after judges ordered the parties to negotiate a “commercial rate”. But the watchdog has proposed a rate of 2

Delivery firm DPD accused of ‘revenge’ sacking drivers who criticised pay cuts
The delivery firm DPD has been accused of “revenge” sackings after workers spoke out against a plan to cut thousands of pounds from their earnings, including their Christmas bonus.The company, which reported pre-tax profits of nearly £200m last year and plays a significant role in the festive rush to have gifts and parcels delivered, has even threatened to withhold money from some staff to pay for the cost of replacing them, the Guardian has learned.DPD confirmed it had dismissed workers after an estimated 1,500 self-employed drivers chose not to take on any work for a three-day period in protest at the plans.It emerged earlier this month that the company had told workers it planned to cut 65p from the rate it pays for most of its deliveries on 29 September.Drivers said the cut, which came to as much as £25 a day, and the loss of a £500 Christmas bonus, was likely to add up to more than £6,000 a year for each worker – and as much as £8,000 for those who take on a lot more deliveries over Christmas

Kimberly-Clark to buy Tylenol maker Kenvue in landmark $40bn merger
Kleenex and Huggies maker Kimberly-Clark unveiled plans to buy Kenvue, the embattled consumer health conglomerate behind Tylenol, in a landmark deal for more than $40bn.The blockbuster takeover comes weeks after Donald Trump claimed Tylenol heightens the risk of autism in children when it is used by pregnant women, an assertion hotly contested by scientists and contradicted by studies.The high-profile claims compounded months of struggles for Kenvue, which ousted its CEO in July and endured sharp stock market declines.Kenvue, which also makes Listerine mouthwash, Neutrogena skincare products and Johnson’s baby oil, was spun out of Johnson & Johnson two years ago. Its shares jumped 17% on Monday morning, while Kimberly-Clark dropped 12% in New York

Pornography depicting strangulation to become criminal offence in the UK

NHS hospitals to test AI tool that helps diagnose and treat prostate cancer

How scientists are shining light on the biology behind seasonal affective disorder

Drone-blocking technology ‘urgently’ required at jails in England and Wales

UK’s unregulated pregnancy scan clinics putting lives in danger, say experts

Why we must tackle the crisis in end-of-life care | Letters