‘Gamechanging’ HIV prevention jab to be approved for England and Wales

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A “gamechanging” injection to prevent HIV is to be approved for use in England and Wales.The long-acting jab, administered every two months, will offer an alternative to the daily pills used to protect against the virus.This form of HIV prevention therapy, known as Prep (pre-exposure prophylaxis), is typically taken by HIV-negative people to reduce their risk of infection.In draft guidance published on Friday, the National Institute for Health and Care Excellence (Nice) recommended cabotegravir (CAB-LA) for adults and young people at risk of HIV who are unable to take oral Prep.The injection is already available on the NHS in Scotland.

The health secretary, Wes Streeting, said the approval of the injection was “gamechanging”.“For vulnerable people who are unable to take other methods of HIV prevention, this represents hope,” he said.“We’re making real progress on HIV, with Prep use up by 8% this year, and our ambition goes even further.England will be the first country to end HIV transmissions by 2030, and this breakthrough treatment is another powerful tool in our arsenal to reach that crucial goal.”The rollout is expected to begin about three months after Nice publishes its final guidance later this year.

More than 111,000 people accessed Prep in sexual health clinics in England in 2024, according to the UK Health Security Agency (UKHSA), a 7% increase over the previous year,Helen Knight, the director of medicines evaluation at Nice, said HIV “remains a serious public health challenge, but we now have powerful tools to prevent new infections”,“Around 1,000 people in England cannot have daily oral Prep due to medical contraindications or other barriers which is why this injection offers an effective option for this community,” she said,Up to 1,000 people are expected to benefit from the new treatment in England a year, according to Nice,
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UK MPs warn of repeat of 2024 riots unless online misinformation is tackled

Failures to properly tackle online misinformation mean it is “only a matter of time” before viral content triggers a repeat of the 2024 summer riots, MPs have warned.Chi Onwurah, the chair of the Commons science and technology select committee, said ministers seemed complacent about the threat and this was putting the public at risk.The committee said it was disappointed in the government’s response to its recent report warning social media companies’ business models contributed to disturbances after the Southport murders.Replying to the committee’s findings, the government rejected a call for legislation tackling generative artificial intelligence platforms and said it would not intervene directly in the online advertising market, which MPs claimed helped incentivise the creation of harmful material after the attack.Onwurah said the government agreed with most of its conclusions but had stopped short of backing its recommendations for action

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The teamwork behind Bletchley Park’s Colossus computer | Letter

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Olivia Williams says actors need ‘nudity rider’-type controls for AI body scans

Actors should have as much control over the data harvested from scans of their body as they do over nudity scenes, the actor Olivia Williams has said, amid heightened concern over artificial intelligence’s impact on performers.The star of Dune: Prophecy and The Crown said she and other actors were regularly pressed to have their bodies scanned by banks of cameras while on set, with few guarantees about how the data would be used or where it would end up.“A reasonable request would be to follow the precedent of the ‘nudity rider’,” she said. “This footage can only be used in the action of that scene. It cannot be used in any other context at all, and when the scene has been edited it must be deleted on all formats

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‘Legacies condensed to AI slop’: OpenAI Sora videos of the dead raise alarm with legal experts

Last night I was flicking through a dating app. One guy stood out: “Henry VIII, 34, King of England, nonmonogamy”. Next thing I know, I am at a candlelit bar sharing a martini with the biggest serial dater of the 16th century.But the night is not over. Next, I am DJing back-to-back with Diana, Princess of Wales

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Dan and Phil’s relationship revelation is a reminder of how toxic fandoms can be | Eilish Gilligan

This week, longtime British YouTubers Dan Howell and Phil Lester uploaded a new video confirming they have been in a secret romantic relationship for the past 16 years.If you weren’t a deeply online child during the 2010s, you probably have no idea who Dan and Phil are, or why this matters. But to those who formed a robust parasocial bond with the duo – who have more than 13 million collective subscribers on YouTube – this was a revelatory moment. It was also a sobering reminder of the emotional damage that toxic fandoms can wreak on their subjects.Over the course of 45 minutes, Howell and Lester, now in their thirties, share the “apocalyptic constant stress of the Dan and Phil dating conspiracy”, where “fans” subjected them to frenzied speculation for 16 years straight

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Banks need stricter controls to prevent romance fraud, says City regulator

The City regulator has called on banks and payment firms to bring in stricter controls protecting customers from romance fraud after a study showed a number of missed “red flags” that led to people losing huge sums of money.The review by the Financial Conduct Authority (FCA) highlighted one case where someone lost £428,000, another where a customer made 403 payments totalling £72,000 to a fraudster and a case where someone wanted money to transfer cryptocurrency to their “partner” in Iraq.Romance scams, where criminals try to build emotional connections with victims before defrauding them, have been growing in scale and complexity in recent years.Figures from the City of London police put the loss from romance fraud at £106m last year, although the FCA says the real figure is much higher as many people do not report the crime owing to feelings of shame and stigma.The FCA review of six banks and payment firms looked at how they detect and prevent romance fraud and found large disparities in how victims of fraud were treated