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We need new drugs for mental ill-health | Letter

1 day ago
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It is not only veterans and emergency workers living with post-traumatic stress disorder who could benefit if ministers heed the call from Sir Nick Carter (Ex-British army chief calls on ministers to back MDMA-assisted therapy for veterans, 1 February).Thousands of people who have major mental illness, and those dealing with bereavement and trauma, could be helped too.The shocking lack of progress in developing transformative psychiatric medicines, and a dearth of innovation has left clinicians with few weapons in their armoury to relieve mental pain.Families and people scarred by long-term distress tell us they are desperate for new treatments and therapies.At the Prince of Wales International Centre for Sane Research, our research centre in Oxford, we host clinical trials researching the medical use of innovative interventions such as esketamine and cannabidiol for psychiatric ill-health.

The government must prioritise research into alternative and more effective treatments, rather than relying on drugs invented and first made available over 60 years ago.Marjorie WallaceChief executive, Sane Have an opinion on anything you’ve read in the Guardian today? Please email us your letter and it will be considered for publication in our letters section.
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Rich plums and ripe tomatoes: Australia’s best-value fruit and veg for February

Tomatoes ripe for cooking, cheap watermelon and cucumbers for $2 a piece – but it’s the final call for apricots, cherries and mangoesGet our weekend culture and lifestyle emailJuicy watermelon, deep-purple plums and ripe roma tomatoes are some of the vibrant fruit and veg highlights this month, says Graham Gee, senior buyer at the Happy Apple in Melbourne.“Tomatoes are plentiful, in particular the saucing varieties,” he says. “Roma varieties are sold nice and ripe, ready to make passata.” Cooking tomatoes are roughly $2 a kilo at the Happy Apple, with Australian field tomatoes going for about $5 a kilo in supermarkets.Watermelon is “very cheap”, says Michael Hsu, operational manager at Sydney’s Panetta Mercato

3 days ago
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How to make moreish cookies from store-cupboard odds and ends – recipe | Waste not

I often eat a bag of salty crisps at the same time as a chewy chocolate bar, alternating bite for bite between the two, because the extreme contrast of salt from the chips and the sweetness of the chocolate fire off each other and create an endorphin rush. The same goes for these cookies, adapted from a recipe by Christina Tosi at New York’s legendary Milk Bar.Christina Tosi writes in Gourmet Traveller Australia how she first learned to make these cookies at a conference centre on Star Island, New England, where they’d bake them each week with a hodge-podge of different ingredients. Being on an island, they didn’t always have access to what they wanted, so they had to come up with a new recipe every week using whatever they had. In the spirit of the recipe’s origins, I’ve adapted Tosi’s recipe for the UK, and made it flexible, so you can raid your own store-cupboards and adapt and invent your own version from it

3 days ago
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Camilla Wynne’s recipes for blood orange marmalade and no-bake marmalade mousse tart

If you’re intimidated by making marmalade, the whole-fruit method is the perfect entry point. Blood oranges are simmered whole until soft, perfuming your home as they do so, then they’re sliced, skin and all, mixed with sugar and a fragrant cinnamon stick, and embellished with a shot of amaro. Squirrel the jars away for a grey morning, give a few to deserving friends, and be sure to keep at least one to make this elegant mocha marmalade mousse tart. A cocoa biscuit crust topped with a chocolate marmalade mousse and crowned with a cold brew coffee cream, it’s a delightful trifecta of bitterness that no one will ever guess is an easy no-bake dessert.If you’re not up for preserving, make this using shop-bought thick-cut marmalade

3 days ago
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The dump dinner: spaghetti is now being served straight on to the table – but why?

Name: Dump dinners.Age: Horribly new.Appearance: Feeding time at the zoo, but for humans.I’ve just Googled this. Apparently a dump dinner is a make-ahead slow cooker recipe

3 days ago
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Australian supermarket coconut water taste test: ‘Smells like an island holiday’

Overcoming his irrational fear of coconut products, Nicholas Jordan tests a lovely – and lowly – bunch of coconuts in a rowIf you value our independent journalism, we hope you’ll consider supporting us todayGet our weekend culture and lifestyle emailI have a fear of coconut products. Like all fears it’s based on a questionable rationale and trauma, and my trauma is taste testing “health” coconut-heavy products that taste like soap. Which is why, until recently, almost all the coconut water I’d drunk was from a straw reaching out of a fresh coconut.Surely there’s no way a bottled coconut water, made from 100% coconut, could be that bad. Maybe it could be better than the real thing? I enjoy Melona more than the average honeydew melon

4 days ago
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Miso mystery: red, white or yellow – how does each paste change your dish? | Kitchen aide

What’s the difference between white and red miso, and which should I use for what? Why do some recipes not specify which miso to use? Ben, by email“I think what recipe writers assume – and I’m sure I’ve written recipes like this – is that either way, you’re not going to get a miso that’s very extreme,” says Tim Anderson, whose latest book, JapanEasy Kitchen: Simple Recipes Using Japanese Pantry Ingredients, is out in April. As Ben points out, the two broadest categories are red and white, and in a lot of situations “you can use one or other to your taste without it having a massive effect on the outcome of the dish”.The Guardian’s journalism is independent. We will earn a commission if you buy something through an affiliate link. Learn more

4 days ago
societySee all
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Alton Towers to test excluding people with autism and ADHD from disability fast lane

1 day ago
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We need new drugs for mental ill-health | Letter

1 day ago
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Violence is part and parcel of how prisons function | Letter

1 day ago
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Blanket rule on trans women in men’s prisons would deny their identity, says Scottish government

1 day ago
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Does getting cold increase your chances of catching flu?

2 days ago
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Autistic girls much less likely to be diagnosed, study says

2 days ago