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The UK’s pharma deal was vital – but the GSK boss is right about US dominance | Nils Pratley

That’s gratitude, eh? It’s not even a fortnight since the government agreed to raise the prices the NHS pays for new medicines and here comes the boss of GSK, Britain’s second largest pharma firm, to extol the virtues of doing business in the US.The US is “still the leading market in the world in terms of the launches of new drugs and vaccines”, said the chief executive, Emma Walmsley, in a BBC interview, explaining why GSK invests about three times as much over there as it does at home. Alongside China, the US is also “the best market in the world to do business development”.Her comments have caused a stir but, actually, are merely a statement of reality. It would be absurd to pretend the UK has suddenly shot to the top of the competitiveness table in life sciences as a result of the multipronged price and tariffs deal at the start of this month

about 12 hours ago
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Disappointing Oracle results knock $80bn off value amid AI bubble fears

Oracle’s shares tumbled 15% on Thursday in response to the company’s quarterly financial results, disclosed the day before.Roughly $80bn vanish from the value of the business software company co-founded by Donald Trump ally Larry Ellison, falling from $630bn (£470bn) to $550bn and fuelling fears of a bubble in artificial intelligence-related stocks. Shares in the chipmaker Nvidia, seen as a bellwether for the AI boom, fell after Oracle’s.The drop extended a 11.5% fall during after-hours trading that followed results shwoing a lower-than-expected 14% rise in revenues to $16bn in the latest quarter

about 13 hours ago
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Musk calls Doge only ‘somewhat successful’ and says he would not do it again

Elon Musk has said the aggressive federal job-cutting program he headed early in Donald Trump’s second term, known as the “department of government efficiency” (Doge), was only “a little bit successful” and he would not lead the project again.Musk said he wouldn’t want to repeat the exercise, talking on the podcast hosted by Katie Miller, a rightwing personality with a rising profile who was a Doge adviser and who is married to Stephen Miller, Donald Trump’s hardline anti-immigration deputy chief of staff.Asked whether Doge had achieved what he’d hoped, Musk said: “We were a little bit successful. We were somewhat successful.”Doge created chaos and distress in the government machine in Washington DC, and by May more than 200,000 federal workers had been laid off and roughly 75,000 had accepted buyouts as a result of purges by Musk’s external team of often-young zealots

1 day ago
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ICE is using smartwatches to track pregnant women, even during labor: ‘She was so afraid they would take her baby’

Pregnant immigrants in ICE monitoring programs are avoiding care, fearing detention during labor and deliveryIn early September, a woman, nine months pregnant, walked into the emergency obstetrics unit of a Colorado hospital. Though the labor and delivery staff caring for her expected her to have a smooth delivery, her case presented complications almost immediately.The woman, who was born in central Asia, checked into the hospital with a smartwatch on her wrist, said two hospital workers who cared for her during her labor, and whom the Guardian is not identifying to avoid exposing their hospital or patients to retaliation.The device was not an ordinary smartwatch made by Apple or Samsung, but a special type that US Immigration and Customs Enforcement (ICE) had mandated the woman wear at all times, allowing the agency to track her. The device was beeping when she entered the hospital, indicating she needed to charge it, and she worried that if the battery died, ICE agents would think she was trying to disappear, the hospital workers recalled

1 day ago
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Can a nepo baby be an underdog? The remarkable rise of Shedeur Sanders

The quarterback was seen as living off his father’s name when he entered the NFL. But he has slowly started to prove himself at the Cleveland BrownsIt seems the goalposts are always moving on Shedeur Sanders, the Cleveland Browns’ rookie quarterback who keeps throwing people off.He excelled at two colleges to establish himself as a top NFL prospect, only to wind up getting picked in the fifth round of this year’s NFL draft in one of the most dramatic stock crashes in league history. He then distinguished himself in training camp, only to wind up as the back-up to the back-up. When Sanders was finally pressed into injury relief duty last month and led the Browns to just their third win of the season, the caveat was that his breakthrough had come at the expense of the even-worse Las Vegas Raiders

about 18 hours ago
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‘The netball mum community has been insane’: England captain Nat Metcalf on her return to action

Receiving her first centre pass at London’s Copper Box Arena will be an unforgettable moment for the skipperA gurgle turns into a squawk, and the early throes of a weary cry – sure-fire signs that an afternoon nap is required. For much of her life, since her dramatic arrival in the pre-dawn hours of a May morning, the seven-month-old Miller has been a regular presence at England netball camps.Sometimes she sleeps courtside, other times watches from a balcony, or is passed between arms of players and staff members eagerly seeking a cuddle during team meetings. Whatever it takes for her mother, the England netball captain, Nat Metcalf, to get back on court.When Metcalf pulls on her England dress against Jamaica on Saturday, returning to competition for the first time since giving birth, Miller will be there, just as she always is

about 19 hours ago
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Sports Personality of the Year 2025: Lionesses square off on six-strong shortlist

about 23 hours ago
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‘It can be brutal’: Gian van Veen learns to fly with the stars after dartitis

about 23 hours ago
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‘Dadgummit, let’s freaking go’: 44-year-old grandfather Rivers could start for Colts

1 day ago
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NHL warns top players will not show up for Winter Olympics if venue is unsafe

1 day ago
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Mets all-time home run leader Pete Alonso reportedly agrees $155m deal with Orioles

1 day ago
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Etzebeth accepts 12-week ban but claims eye-gouge ‘was never intentional’

1 day ago

Christmas gift ideas for drinks lovers, from champagne to canned cocktails

about 19 hours ago
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Don’t get pulled in by silly gadgets: buy presents you’d be happy to receive yourselfThe Guardian’s journalism is independent.We will earn a commission if you buy something through an affiliate link.Learn more.Alcohol is an unavoidable part of a festive spread (for more advice on which wines, beers and other drinks I like for each and every occasion, take a look at last week’s Christmas drinks guide), but, sometimes, a drink deserves a place under the tree as well as around it – especially if it’s an easy win for a drinks devotee for whom you need to buy a prezzie.The Guardian’s journalism is independent.

We will earn a commission if you buy something through an affiliate link.Learn more.As I said at this time last year, don’t waste your time and money on fancy-dan wine kit and gadgets: I am speaking for myself here, of course, but a lot of it will ultimately find its way to a kitchen drawer, never to be seen again.I am always running out of corkscrews, however, and the one from St John is iconic and monochrome, or maybe something sleek and silver from Fortnum & Mason, perhaps?When it comes to gifting wine, it’s a good idea to draw on the crowdpleasers to fit that specific bill.For sparkling wines, crémant is a cost-effective option if you want the delight of fizz but don’t have deep pockets.

Champagne, even in a supermarket, teeters around the £50-mark these days, though there are some cute gift boxes out there to warrant the expense: Piper Heidsieck’s fire hydrant case is fun and camp, and there’s no better excuse than Christmas to break out Veuve Cliquot’s puffy bottle holder.But if buying booze feels like too much of a minefield (drinks aficionados can be exacting types), some good stemware is a nice option, because it’s thoughtful, good-quality stuff can be had at every price point, and it’s a gift that will allow a wine lover to get the most out of wine they already have.To that end, I really, really recommend the stemware from Zara Home: most ready-to-buy fashion homeware sections are all thick glass and style over ergonomics, but much of Zara’s range is chic and purpose-built.Its Bohemia crystal plain glass, for instance, made up my first home set, and is a snip at £4.99 each.

With a wide base to swirl your wine and a narrow rim to collect the aromas, it’s a great vessel to enjoy your wine in.You’ll also find matching tumblers and flutes online.At the crazier end, Maison Balzac makes some truly zany stemware designed with your favourite beverages in mind: blown-glass chillies, for instance, adorn one short tumbler, surely created to house a spicy margarita.And it’s spenny, yes, but the original universal wine glass from Richard Brendon’s collaboration with Jancis Robinson is an excellent luxury option, too.Emphasis on the luxury here – they’re £96 for two – but if anyone is looking to get me anything for Christmas, my housemate has managed to smash two.

I’ll also accept gift cards.Piper Heidsieck Code Rouge Gift Set £65.99 Selfridges, 12%.So silly and brilliant: Piper’s classic cuvée in a container shaped like a fire extinguisher.Whitebox Cocktails Spicy Marg Cracker £12 Whitebox Cocktails, 20.

5%.A stocking filler if ever I saw one: two 100ml cans of spicy marg.The King’s Ginger £32.50 (50cl) Berry Bros & Rudd, 29.9%.

I do not like hunting, with which this is associated, but I do like winter walks,Sip this warming gingery liqueur from a flask,Craft Beer Case £39 (12 x 330ml) The Wine Society, various ABVs,A range of IPAs, lagers and porters for the beer-drinker in your life,