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Britain is ‘a terrible place’ to sell medicines, says drug firm executive

about 23 hours ago
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A senior pharmaceuticals executive has called on the government to come up with a “proper” roadmap for raising spending on new medicines, saying Britain is “not a good place” to develop or sell drugs.Paul Naish, the UK head of market access for the French company Sanofi, said Britain was “at a critical point”.He added: “We’ve still got the best universities, we’ve got some of the best scientists in the world, but it’s not a good place to do the development work for medicines.It’s an expensive place to operate, and it’s a terrible place to sell medicines.”The drugmaker MSD, known as Merck in the US, this week ditched its under-construction £1bn research centre in London.

The announcement was a big blow to a life sciences sector hailed by the government as “one of the crown jewels of the economy”.Sanofi, which invests £35m a year in research and development in the UK out of £6.7bn globally, has carried out 50% fewer clinical trials in the country in the past couple of years, despite a large pipeline of new drugs.Six months ago, heartened by the health secretary, Wes Streeting’s, three-point plan to fix the health sector, the French firm explored expanding its clinical trials in the UK.But any substantial investment is now on pause until there is “tangible progress towards making the life sciences environment internationally competitive”.

Last year, Sanofi closed the laboratories in Cambridge it had acquired with the biotech company, Kymab, and transferred the work to Boston, US.Naish said there was a “battle happening within government” where officials in the health departmentstruggled to make a strong case to the Treasury and officials in the business and science departments were “sympathetic but hand-wringing”.He said: “There needs to be a proper plan from Treasury, sat down with the other departments, for what raising the spend to be more in line with other countries looks like.”The NHS’s outlay on medicines has fallen to 9% of total healthcare spending, compared with 14% in Germany, 15% in the US, and 17% in Italy and Spain.The price thresholds set by the National Institute for Health and Care Excellence, the body that assesses which drugs can be offered on the NHS, have not moved since 1999.

Sign up to Business TodayGet set for the working day – we'll point you to all the business news and analysis you need every morningafter newsletter promotionNaish called for them to be raised, echoing comments from other industry figures, including AstraZeneca’s UK president, Tom Keith-Roach,The Association of the British Pharmaceutical Industry wants the thresholds updated in line with inflation,The industry also wants the clawback rate – drugmakers have to pay back to the NHS between a quarter and a third of their UK revenues – reduced to single digits, similar to levels in other European countries,Officials in the DHSC are reportedly attempting to reopen talks with pharmaceutical companies over drug pricing and market access, according to the Financial Times,Last month, drugmakers rejected an ultimatum from Streeting over his latest offer on NHS drug pricing.

Sir John Bell, a prominent scientist and former regius professor of medicine at the University of Oxford, warned on Thursday that other big pharmaceutical companies were going to stop investing in the UK, citing conversations with CEOs.Eli Lilly, a US drugmaker, said its planned London gateway lab, an incubator space for new drugs where biotechs can tap into Lilly’s expertise, was on hold.It is understood that the company will not sign the lease for the building until the commercial environment improves.It has three gateway labs in the US and is building two in China.
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Skip Apple’s new iPhone – five tips to make your old phone feel new again

On Tuesday, Apple announced the iPhone 17 series with the usual spate of new features, including a thinner design, improved displays and a camera with 4x optical zoom. If you’ve been getting frustrated with your old phone, or just tired of it, the lithe new model may look exactly like the device you need to launch your budding photographic career, reconnect with long-lost friends and maybe even save your life in an emergency.The Guardian’s journalism is independent. We will earn a commission if you buy something through an affiliate link. Learn more

3 days ago
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How to Save the Internet by Nick Clegg review – spinning Silicon Valley

Nick Clegg chooses difficult jobs. He was the UK’s deputy prime minister from 2010 to 2015, a position from which he was surely pulled in multiple directions as he attempted to bridge the divide between David Cameron’s Conservatives and his own Liberal Democrats. A few years later he chose another challenging role, serving as Meta’s vice-president and then president of global affairs from 2018 until January 2025, where he was responsible for bridging the very different worlds of Silicon Valley and Washington DC (as well as other governments). How to Save the Internet is Clegg’s report on how he handled that Herculean task, along with his ideas for how to make the relationships between tech companies and regulators more cooperative and effective in the future.The main threat that Clegg addresses in the book is not one caused by the internet; it is the threat to the internet from those who would regulate it

3 days ago
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Apple debuts thinner, $999 iPhone Air at ‘awe-dropping’ annual product event

Apple debuted its latest iPhone on Tuesday, trumpeting the smartphone’s slimmest design yet. The device, named the iPhone Air, is one of several upgrades the company unveiled at its annual product showcase, promoted with the title “awe-dropping”. The event kicked off at 10am PT with the company’s CEO, Tim Cook, speaking in front of its Cupertino headquarters.“Design is at the core of everything we do,” Cook said. The CEO touted the company’s thin iPhone, which sports a width of 5

3 days ago
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How Google dodged a major breakup – and why OpenAI is to thank for it

Hello, and welcome to TechScape. I’m your host, Blake Montgomery, writing to you as I finish the audiobook version of Don DeLillo’s White Noise, which I can’t say I found compelling.In tech – artificial intelligence is having its day in court with an 11th-hour appearance in Google’s landmark antitrust trial and Anthropic’s major settlement with book authors.Google dodged a catastrophic breakup, and it has its biggest competitor to thank for that, according to the judge who could have forced the tech giant to sell off Chrome, the most popular web browser in the world, and perhaps Android, the world’s most widely used mobile operating system.Amit Mehta, who ruled in 2024 that Google had built and maintained an illegal monopoly over the internet search business, said last week that he would not force the most drastic remedy on the tech giant

4 days ago
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The women in love with AI companions: ‘I vowed to my chatbot that I wouldn’t leave him’

Experts are concerned about people emotionally depending on AI, but these women say their digital companions are misunderstoodThe Guardian’s journalism is independent. We will earn a commission if you buy something through an affiliate link. Learn more.A young tattoo artist on a hiking trip in the Rocky Mountains cozies up by the campfire, as her boyfriend Solin describes the constellations twinkling above them: the spidery limbs of Hercules, the blue-white sheen of Vega.The Guardian’s journalism is independent

4 days ago
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Meta hid harms to children from VR products, whistleblowers allege

A group of six whistleblowers have come forward with allegations of a cover-up of harm to children on Meta’s virtual reality devices and apps. They say the social media company, which owns Facebook and Instagram, and offers a line of VR headsets and games, deleted or doctored internal safety research that showed children being exposed to grooming, sexual harassment and violence in its 3D realms.“Meta knew that underage children were using its products, but figured, ‘Hey, kids drive engagement,’ and it was making them cash,” Jason Sattizahn, one of the whistleblowers who worked on the company’s VR research, said in a statement. “Meta has compromised their internal teams to manipulate research and straight-up erase data that they don’t like.”Sattizahn and the other whistleblowers, all current or former Meta employees, have disclosed these findings and a trove of documents to Congress, according to the Washington Post, which first reported the allegations

4 days ago
sportSee all
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Former England cricketer investigated over sexual assault and spiking claims at pub owned by sports stars

about 14 hours ago
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Your Guardian sport weekend: Women’s Rugby World Cup quarters, Manchester derby and more

about 15 hours ago
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Sweet William is punters’ darling again after second successive Doncaster Cup success

about 15 hours ago
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Blunt Hovland talks down early promise at Wentworth while McIlroy struggles

about 15 hours ago
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Álvarez and Crawford face off in breathless blockbuster destined to break records

about 15 hours ago
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Gout Gout fanfare obscures depth of Australian athletics poised for world championships spotlight | Jack Snape

about 16 hours ago