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Big pharma will stop investing in UK, top scientist warns after Merck’s £1bn exit

2 days ago
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Sir John Bell, a prominent scientist who brought business and government together during the Covid-19 vaccine rollout, has warned that other big pharmaceutical companies will stop investing in the UK, after the US drugmaker MSD’s decision to scrap its planned £1bn London research centre.Bell, a former regius professor of medicine at the University of Oxford, told Today on BBC Radio 4 that he had spoken to several chief executives of large companies in the past six months and that they were “all in the same space.And that is: they’re not going to do any more investing in the UK.”He made the comments a day after MSD, known as Merck in the US, said it would pull out of research & development (R&D) in the UK with the loss of 125 science jobs, citing Britain’s lack of progress on life science investment and the “overall undervaluation of innovative medicines and vaccines by successive UK governments”.The Canadian immunologist, who was an early member of the government’s vaccine taskforce and previously worked on Oxford University’s Covid vaccine with AstraZeneca, said: “This is a sign of something which has been evolving over a little while, but it’s going to now, I think, lead to a whole series of events which will mean that the industry is going to stop investing in the UK.

”He said the pharma industry was “in real trouble in terms of pricing, particularly in America”, where Donald Trump has put pressure on companies to lower prices, and not to sell medications at a much lower price elsewhere.A big issue is the amount of money the NHS spends on medicines, Bell said.“Ten years ago, we used to spend 15% of our healthcare spend on pharmaceuticals.Now it’s 9%.The rest of the world, the OECD, are sitting between 14% and 20%,” he added.

Long-running negotiations between the UK government and drugmakers over the cost of medicines broke down last month.Under the voluntary pricing and access scheme, companies agree to pay back to the NHS a certain amount of their UK revenue made from branded drugs.They are now paying back between one-quarter and one-third of their UK revenue (23.5% to 35.6%), compared with rebate rates of 5.

7% in France and 7% in Germany, according to the Association of the British Pharmaceutical Industry.Bell said Britain had “great science in academia” and “great biotech companies” and infrastructure funded by government, “but without large companies, it isn’t going to work”.He added: “The large companies do have to work in a system where they can sell their products, and if they can’t sell their products here, they’ll go and do their business somewhere else.”The science minister, Ian Murray, told MPs in the Commons that MSD’s decision was “deeply disappointing and a commercial decision for them” but added that it was part of global cost cuts.He pointed to changes in “US and international fundamentals” that were affecting the life sciences sector.

Sign up to Business TodayGet set for the working day – we'll point you to all the business news and analysis you need every morningafter newsletter promotionMurray said the fall in NHS spending on medicines was due to previous Conservative governments: it declined from 15% of overall healthcare spending to 9% in the last 15 years.Sharon Todd, chief executive of the Society of Chemical Industry, said the loss of MSD’s R&D operations in the UK and reports that AstraZeneca could jump ship to the US “should be setting off alarm bells in government”.She added: “The growing exodus of large-scale businesses from the UK is immensely alarming.Science-based businesses such as pharmaceutical and chemical companies have not only a rich, proud heritage in Britain, but are critical to driving growth in the economy and building our national resilience.”Bell said the UK had been in this situation before, and “solved [the problems] by being a bit more creative for what we did”.

He referred to the cancer drugs fund, introduced in 2011 by David Cameron, then prime minister.The UK had fallen behind on cancer medicinesand the fund enabled it to buy innovative, more expensive drugs.Bell has just stood down as president of the Ellison Institute of Technology, founded by the US billionaire Larry Ellison, who briefly overtook Elon Musk as the world’s richest man on Wednesday.At the start of this month the institute launched a new AI vaccine research programme with Oxford.The best public interest journalism relies on first-hand accounts from people in the know.

If you have something to share on this subject you can contact the Business team confidentially using the following methods,Secure Messaging in the Guardian appThe Guardian app has a tool to send tips about stories,Messages are end to end encrypted and concealed within the routine activity that every Guardian mobile app performs,This prevents an observer from knowing that you are communicating with us at all, let alone what is being said,If you don't already have the Guardian app, download it (iOS/Android) and go to the menu.

Scroll down and click on Secure Messaging.When asked who you wish to contact please select the Guardian Business team.SecureDrop, instant messengers, email, telephone and postIf you can safely use the tor network without being observed or monitored you can send messages and documents to the Guardian via our SecureDrop platform.Finally, our guide at theguardian.com/tips lists several ways to contact us securely, and discusses the pros and cons of each.

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Former England cricketer investigated over sexual assault and spiking claims at pub owned by sports stars

A former England cricketer is being investigated by police over an allegation of sexual assault and claims two women had their drinks spiked at a London pub co-owned by a group of current and former sport stars.In a statement released to the Daily Telegraph on Friday, the Metropolitan police confirmed that officers interviewed a man in his 40s in June after it received a complaint about an alleged spiking and assault.“Two women are believed to have been spiked with one also allegedly sexually assaulted,” the statement read. “A man in his 40s was interviewed under caution on Thursday, June 5. Enquiries remain ongoing and no arrests have been made at this stage

about 19 hours ago
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Your Guardian sport weekend: Women’s Rugby World Cup quarters, Manchester derby and more

Tom Bassam has all the buildup to Saturday’s bumper football action. He’ll spin through the headlines and look ahead to eight Premier League fixtures, with team news and breaking stories. First action of the day is the lunchtime kick-off at the Emirates Stadium, where Arsenal host Nottingham Forest and English football welcomes back its favourite not-for-turning Aussie. Ange Postecoglou is back in work after replacing Nuno Espírito Santo at the City Ground, less than three months after leaving Spurs. David Hytner and Barney Ronay provide expert reports and analysis, with Rob Smyth providing online coverage

about 19 hours ago
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Sweet William is punters’ darling again after second successive Doncaster Cup success

There are horses that win with a minimum of fuss, and others, like Sweet William, that have a style that is all their own, and John & Thady Gosden’s stayer kept it interesting throughout in the Doncaster Cup on Friday, as he overcame a slow start and some early coaxing from Rab Havlin in his saddle to win the Group Two contest for the second year running.Sweet William has often appeared to have his own ideas about the racing game during a 20-race career, with slow starts and mid-race flat spots frequently forcing Havlin to get busy at an early stage.When he eventually goes through the gears, however, he is a very difficult horse to keep out of the frame, and while his latest win was his first since the same race 12 months ago, his fourth-place finish in this year’s Ascot Gold Cup was the only time he has been outside the first three. His strike-rate for each-way backers is 85%.Sweet William was bumped leaving the stalls, took a few strides to find his balance and was then ridden by Havlin to make up the lost ground before tacking himself on at the back of the field

about 19 hours ago
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Blunt Hovland talks down early promise at Wentworth while McIlroy struggles

It is difficult to square Viktor Hovland’s excellent position on the Wentworth leaderboard with the Norwegian’s blunt assessment of his game. The 27-year-old claimed he hit certain shots on the West Course on Friday that “hurt my soul”.Hovland has been in a state of technical flux all year, with his driving a particular cause for concern. He is perfectly candid about that, despite rounds of 67 and 66 at this PGA Championship. Hovland’s next start will come as part of team Europe in the Ryder Cup

about 19 hours ago
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Álvarez and Crawford face off in breathless blockbuster destined to break records

More than 70,000 spectators will witness oversized fight but smallest margins will decide outcome Las Vegas has staged its share of blockbuster fight nights but nothing on the scale of what is coming this weekend. On Saturday night at Allegiant Stadium, the $2bn (£1.47bn) home of the NFL’s Raiders, Saúl “Canelo” Álvarez will defend his undisputed super-middleweight crown against Terence Crawford in front of more than 70,000 spectators, by far the largest boxing crowd the city has ever seen.Millions more will watch on Netflix, which is carrying the card at no extra cost to subscribers – a first for a fight of this magnitude and a reminder of how the business of boxing is being remade in real time. For decades, the sport depended on pay-per-view

about 20 hours ago
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Gout Gout fanfare obscures depth of Australian athletics poised for world championships spotlight | Jack Snape

The sudden rise of sprint phenomenon Gout Gout has triggered an explosion of interest in athletics, but it has also obscured the sport’s growing depth in Australia, which is poised for the spotlight at the world championships in Japan starting on Saturday.Despite the hype, Gout is far from Australia’s best chance of success in the hot and humid National Stadium in inner Tokyo. The team totals 86 athletes – 22 more than in Budapest in 2023 – and Australia has never sent a larger group to a global meet. There are as many as 10 genuine medal contenders, including 21 Australian athletes seeded higher than the Brisbane high school student.The teenager’s seeding of 16 suggests he will do well just to make it to the semi-finals and remain competitive in his first major meet, alongside the likes of Noah Lyles, Letsile Tebogo, Kenny Bednarek and the rest of the world’s fastest men, even if some – including veteran commentator Bruce McAvaney and fellow sprinter Lachlan Kennedy – believe he could go all the way to the final

about 21 hours ago
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Skip Apple’s new iPhone – five tips to make your old phone feel new again

3 days ago
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How to Save the Internet by Nick Clegg review – spinning Silicon Valley

3 days ago
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Apple debuts thinner, $999 iPhone Air at ‘awe-dropping’ annual product event

4 days ago
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How Google dodged a major breakup – and why OpenAI is to thank for it

4 days ago
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The women in love with AI companions: ‘I vowed to my chatbot that I wouldn’t leave him’

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Meta hid harms to children from VR products, whistleblowers allege

5 days ago