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Ozempic maker Novo Nordisk cuts sales and profit forecasts again

about 5 hours ago
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The maker of Ozempic and Wegovy has cut its sales and profit forecasts as it continues to fall behind in the competitive market for obesity and diabetes treatments.Novo Nordisk’s chief executive, Mike Doustdar, who took the reins in August, said the reduced guidance was because of “the lower growth expectations for our GLP-1 treatments”.“The market is more competitive than ever more,” Doustdar said in a video message accompanying the company’s third-quarter results.The Danish pharmaceutical firm’s rate of profit growth has slowed and its share price has slid after losing ground to its US rival Eli Lilly, which makes the Mounjaro and Zepbound weight-loss injections.Clinical studies have shown that Mounjaro is more effective in causing weight loss than Wegovy.

Novo Nordisk said it now expected full-year operating profit to grow by a maximum 7% in 2025, compared with an earlier forecast of up to 16%.In addition, the company forecasted sales to grow by no more than 11%, at constant exchange rates, compared with a previous forecast of up to 16%.It has cut forecasts four times this year.The company said its third-quarter sales increased by 5% to 75bn Danish kroner (£8.9bn), below the 76.

2bn forecast by analysts, while its sales grew by 11% during the period.Last month, Novo said its chair, Helge Lund, and six other board members were stepping down in a surprise shake-up, after a row with the company’s majority shareholder.In May, it announced Lars Fruergaard Jørgensen would be stepping down as chief executive.The Danish drugmaker is also locked in a tussle with the drugmaker Pfizer to buy the US obesity-focused biotech firm Metsera.In late October, Novo launched a surprise $9bn (£6.

9bn) offer, which threatened an existing bid from Pfizer.Both companies have since submitted improved offers for Metsera as the two companies fight for dominance in the lucrative weight-loss market.Pfizer previously requested a temporary restraining order in a US court, looking to stop Novo’s bid.This was rejected by a judge in Delaware.A further hearing has been scheduled for Wednesday.

Sign up to Business TodayGet set for the working day – we'll point you to all the business news and analysis you need every morningafter newsletter promotionMetsera is considered a desirable takeover target in part because of its promising pipeline of obesity drugs.The company has four ongoing clinical trials, including a weight-loss pill, a monthly injection, and two drugs that promote the sensation of feeling full.Derren Nathan, the head of equity research at the investment platform Hargreaves Lansdown, said: “Novo Nordisk’s CEO Mike Doustdar’s first set of results in the hot seat have come with slimmed down guidance for the full year.Hardly an ideal start but better for him to cut now while fingers can still be pointed at legacy issues.“The contrast in these results to knockout third-quarter numbers from arch-rival Eli Lilly highlights the scale of the task for the new captain to turn the ship around.

”Novo’s share price has halved this year and the drugmaker, which remains one of Europe’s largest companies, has cut 9,000 jobs.
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Marks & Spencer profits more than halve after cyber-attack

Profits at Marks & Spencer have more than halved after a damaging cyber-attack that is still affecting its struggling clothing and homeware business.The retailer said underlying profits fell to £184.1m in the six months to 27 September, from £413.1m a year before, after it had to halt online orders of clothing and homewares for more than six weeks.Clothing and homeware sales were down 16

about 8 hours ago
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Fixing Britain’s worklessness crisis will cost employers £6bn a year, report says

Employers have been told in a landmark government review that fixing Britain’s health-related worklessness crisis will require them to spend £6bn a year on support for their staff.In a major report before this month’s budget, Charlie Mayfield warned that businesses needed to play a more central role in tackling a rising tide of ill-health that is pushing millions of people out of work.The former chair of John Lewis, who was appointed by ministers to lead the government’s Keep Britain Working review last year, said that a drastic expansion in occupational health was needed to help prevent hundreds of thousands of people from falling out of the workforce each year.“We need to fix this,” Mayfield told the Guardian. “What we are proposing is a fundamental reset in terms of how health is handled in the workplace

about 16 hours ago
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Telecoms companies to improve security to stop UK phone number ‘spoofing’

Six of the biggest phone companies have said they will work together and upgrade their systems to stop fraudsters being able to “spoof” UK phone numbers and commit fraud.New technology is expected to be rolled out over the next year that will stop criminals impersonating legitimate bodies and subsequently duping people into believing they are talking to real companies, banks and government departments.Under the new plans, which aim to tackle number spoofing by foreign call centres, it will become clear when calls are coming from abroad.The agreement – called the second telecommunications fraud charter – is expected to be signed on Wednesday by representatives of BT/EE, Virgin Media O2, VodafoneThree, Tesco Mobile, Talk Talk and Sky as well as Comms Council UK (CCUK), an industry body, and the government.In January, the telecoms regulator Ofcom said phone providers must block all calls from abroad that falsely displayed a UK landline number

about 16 hours ago
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Ashford’s ghost terminal could be brought back to life by Richard Branson | Letters

The decision to end Eurostar’s monopoly on cross-Channel rail shows that Britain is serious about growth (Virgin Trains on track to challenge Eurostar cross-Channel monopoly with access to key depot, 30 October).Far from just being an inter‑city triumph, allowing Virgin Trains to run rival international rail services brings with it the possibility of reopening the abandoned Ashford International terminal. Opened with £80m of investment, it has been a ghost terminal since Eurostar stopped trains there in 2020.Gathering dust, it has been a symbol of a country that had turned inwards, leaving businesses, tourism and people on the south coast poorer. Research from the Good Growth Foundation shows reopening it would boost our local economy by up to £2

about 22 hours ago
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China accuses Dutch of prolonging chip war that threatens to halt car factories

China has told the Netherlands to “stop interfering” in the seized chipmaker Nexperia, accusing it of prolonging a dispute that has disrupted the global car industry.The Dutch government took control of the semiconductor-maker at the end of September amid US security concerns about the company’s Chinese parent, Wingtech Technology.In response, China halted exports of Nexperia products, restricting access to the vital components used in everything from airbags to central locking, and prompting carmakers in the EU, the UK and Japan to issue warnings that supply shortages could lead to stoppages.The EU is in the middle of urgent talks with Beijing to lift export controls on the chips and also on crucial rare earth minerals, after a summit with officials from both sides in Brussels on Friday.On Tuesday, however, China signalled its decisions were still being coloured by the Nexperia dispute, accusing the Dutch of failing to cooperate on export exemptions and urging them to work in a “constructive manner” to ease supply chain issues

about 22 hours ago
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Pound hits lowest since April as investors anticipate budget tax rises; markets hit by AI valuation jitters – as it happened

The pound has now dropped to $1.3064, a new six-month low, as City traders anticipate tax rises in this month’s budget.Sterling has lost more than 0.5% today, or around three-quarters of a cent, with analysts pointing to Rachel Reeves’s promise of an “iron clad” commitment to her fiscal rules, and her failure to rule out tax rises.Fiona Cincotta, senior market analyst at City Index, says:In a rare pre-budget speech, Reeves reiterated her commitment to budget goals and what many are considering as weaves, paving the way for more tax hikes and tough decisions in the Budget that would come close to breaking the party’s manifesto pledges

1 day ago
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OpenAI signs $38bn cloud computing deal with Amazon

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Oakley Meta Vanguard review: fantastic AI running glasses linked to Garmin

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‘History won’t forgive us’ if UK falls behind in quantum computing race, says Tony Blair

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In Grok we don’t trust: academics assess Elon Musk’s AI-powered encyclopedia

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Has OpenAI really made ChatGPT better for users with mental health problems?

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Boom or bubble? Inside the $3tn AI datacentre spending spree

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